Construction of Perloja Church began in 1928, and on October 4, 1930, the newly built church was solemnly consecrated by the Bishop of Kaišiadorys. The brick, single-towered Perloja Church was designed in a late Neo-Romanesque style. The bricks for the construction were made by the parishioners themselves, though many families had to tighten their belts considerably to raise the necessary funds – each farmstead was asked to donate 1,200 Lithuanian litas.

In 1943, the church’s exceptional interior decoration was created by the renowned professor Jurgis Hopenas from the Warsaw Academy of Fine Arts. The church is adorned not only with highly artistic wall paintings but also features numerous national and patriotic symbols – for example, Lithuanian heraldry such as the Columns of Gediminas, the Jogaila Cross, and the Vytis emblem in the keystones of the supporting arches.

Aleksandras Barauskas (1899-1940) – the first victim of the bolshevik occupation of Russia, is buried in the Perloja churchyard.